CorEuStem • COST Action CA20140

The European Network for Stem Cell Core Facilities

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ABOUT

The CorEuStem COST Action

The COST Action CorEuStem – The European Network for Stem Cell Core Facilities is comprised by experts in stem cell biology, differentiation, organoids and gene editing technologies with the aim of developing an efficient and effective consortium for harmonizing procedures and protocols across Europe and beyond. CorEuStem consortium seeks to become a Pan European reference point for stakeholders in stem cell biology and associated technologies.

ABOUT

Introduction to the Action

1

Objectives

The main objective of the CorEuStem is to develop an efficient and effective consortium for harmonizing procedures,  protocols and tools to provide efficient benchmarking, quality control and intensive training.

2

Challenge

One of the major challenges for core facilities is to keep track, evaluate and implement cutting-edge technologies. Core facilities strive to standardize, evaluate, adopt and implement new technologies in the field of hPSCs, organoid biology and gene editing

3

Background

In the past 12 years, experimental approaches used in biomedical research have been reshaped by the discovery of human induced pluripotent stem cells (iPSCs), the development of CRISPR/Cas9 gene editing technology and the possibility of generating in vitro organ-like structures called organoids.

Structure

Meet our Working Groups

WG1 will define the set of protocols to be evaluated and to be put in common from the reprogramming, iPSC maintenance and culture, 2D differentiation and 3D organoids.
WG2 will define the set of protocols, reagents, and procedures to be put in common for the network regarding gene editing and CRISPR/CAS technologies.
WG3 will evaluate, and benchmark the protocols, reagents and procedures used across facilities. WG3 will be the framework that enables this comparison, identifying and establishing standardized best practice with respect to general and quality control procedures, thereby facilitating harmonization through dissemination and adoption.
WG4 will plan, design, develop and organise the training events, workshops on human development activities required for the network.
The objective of WG5 will be to build, grow and strengthen the ties between members of the CorEuStem Action as well as attracting new members.
WG6 will manage and work transversally to integrate and evolve the different technologies and actions in the network, the interactions.

Join the action

Are you
Interested in Taking Part?

The COST Action CorEuStem welcomes research-active scientists working in the field. There are many ways to get involved.

News

Latest Updates

Next CorEuStem webinar will be held November 9th, 2023, 11.00 – 12:00 (CET). Please register here to attend. Speaker: Dr. Leszek LisowskiChildren’s Medical Research Institute (CMRI)The University of Sydney, Australia Dr. Leszek Lisowski is a world vectorology expert with over 15 years of experience in developing and manufacturing viral vectors for human gene therapy. Currently,...

Please join us for the next webinar on “Preclinical testing of CRISPR therapeutics for inherited diseases”. Date: October 6th , 14.00h -15.00h (Berlin time) Speaker: Dr. rer. nat. Lukas Cyganek University Medical Center Göttingen, Germany Please register to attend at:  https://forms.gle/zTPgawWQb9ryAdWC8 Participation by Zoom: To ensure that the meeting is accessible for all CorEuStem members. If you would...

Last weekend, on 9-10 September, it took place the first edition of CorEuStem hands-on iPSC training school at Erasmus Medical Center, in Rotterdam, The Netherlands. The course covered two days of talks and laboratory practice using human iPSC. Students from seven different countries learned how to thaw, split and cryopreserve iPSC, as well as manually...

We invite all CorEuStem members to participate in a two-day online seminar on the Fundamentals of human iPSC culture, September 9-10, 2023. Please register here to receive a Zoom link:  https://forms.gle/JDVGf2AqC96S3k8J8 The seminar program can be fond here.

23 – 24 August 2023 Gene-editors from the CorEuStem network gathered for two days, discussing post-edit quality controls and molecular karyotyping cut-off strategies. The meeting took place at the Lund Stem Cell Centre, thanks to the organising skills of the CAGT team and WG2.

The Standardising Stem Cell Core Facilities in Europe – a CorEuStem Symposium took place at Champalimaud Foundation in Lisbon, Portugal, from 27th to 28th April 2023. The meeting gathered experts from the different core facilities in Europe and covered the latest advances in human stem cells and gene editing technologies. More than 80 participants members attended from CorEuStem COST Action. The two-day...